Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM268Uncharacterized protein. (354 aa)    
Predicted Functional Partners:
TMEM266
Transmembrane protein 266.
      
 0.906
SLC35F4
Solute carrier family 35 member F4.
      
 0.843
CDHR2
Cadherin related family member 2.
      
 0.733
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
      
 0.703
CDK14
Cyclin dependent kinase 14; Belongs to the protein kinase superfamily.
      
 0.703
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
      
 0.666
AIFM1
Apoptosis inducing factor mitochondria associated 1.
      
 0.661
MRC2
Mannose receptor C type 2.
      
 0.641
ATP6V1C1
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
     
 0.636
GTPBP2
GTP binding protein 2.
      
 0.588
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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