Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM9ADAM metallopeptidase domain 9. (782 aa)    
Predicted Functional Partners:
MERTK
MER proto-oncogene, tyrosine kinase.
    
 0.900
SH3PXD2A
SH3 and PX domains 2A.
    
 0.637
CDH1
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.601
HYAL4
Hyaluronidase.
   
 
 0.590
SPAM1
Hyaluronidase.
   
 
 0.590
LOC102349128
Hyaluronidase.
   
 
 0.590
H3BDW1_LATCH
Ion_trans domain-containing protein.
   
  
 0.584
GRB2
Growth factor receptor bound protein 2.
    
 
 0.533
SH3PXD2B
SH3 and PX domains 2B.
    
 0.518
LGI2
Leucine rich repeat LGI family member 2.
     
 0.496
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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