Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NALCNSodium leak channel, non-selective. (1590 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.999
UNC80
Uncharacterized protein.
   
 0.974
H3AAS0_LATCH
Unc-80 homolog (C. elegans).
   
 0.974
FAM155B
Family with sequence similarity 155 member B.
   
 
 0.885
FAM155A
Family with sequence similarity 155 member A.
   
 
 0.885
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.847
H3AMY7_LATCH
Uncharacterized protein.
      
 0.793
SCN1B
Sodium voltage-gated channel beta subunit 1.
   
 0.678
ITSN2
Intersectin 2.
      
 0.675
SCN2B
Sodium voltage-gated channel beta subunit 2.
   
 0.645
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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