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SHPRH protein (Latimeria chalumnae) - STRING interaction network
"SHPRH" - SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHPRHSNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase (1577 aa)    
Predicted Functional Partners:
ASH1L
Ash1 (absent, small, or homeotic)-like (Drosophila) (925 aa)
     
  0.851
SSRP1
Structure specific recognition protein 1 (584 aa)
     
  0.847
TOP2A
Topoisomerase (DNA) II alpha 170kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1569 aa)
     
  0.843
TOP2B
Topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1615 aa)
     
  0.843
BRPF1
Bromodomain and PHD finger containing, 1 (1215 aa)
     
  0.776
BRD1
Bromodomain containing 1 (1190 aa)
     
  0.776
BRPF3
Bromodomain and PHD finger containing, 3 (1194 aa)
     
  0.776
FANCM
Fanconi anemia, complementation group M (2075 aa)
     
  0.702
POLR2B
Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1176 aa)
     
  0.694
EHMT1
Euchromatic histone-lysine N-methyltransferase 1 (1352 aa)
     
  0.674
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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