STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLCB4Phosphoinositide phospholipase C. (919 aa)    
Predicted Functional Partners:
LOC102359416
Uncharacterized protein.
    
 0.987
GNA11
G protein subunit alpha 11.
    
 0.979
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 0.965
PLCB1
Phosphoinositide phospholipase C.
  
  
0.965
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
    
 0.965
H3AW07_LATCH
Ion_trans domain-containing protein.
    
 0.951
GNAI3
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.948
PRKCA
Protein kinase C alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.940
ZFX
Uncharacterized protein.
      
 0.930
DCTN2
Dynactin subunit 2.
      
 0.930
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.