Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102347948Uncharacterized protein. (290 aa)    
Predicted Functional Partners:
AFDN
Afadin, adherens junction formation factor.
    
 0.967
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.956
TJP2
Tight junction protein 2a (zona occludens 2).
   
 0.949
PARD3
Par-3 family cell polarity regulator.
    
 0.928
ITGB2
Integrin beta.
     
 0.928
JAM3
Junctional adhesion molecule 3.
  
 
0.911
RAPGEF6
Uncharacterized protein.
     
 0.911
JAM2
Junctional adhesion molecule 2.
    
0.910
LOC102365550
Uncharacterized protein.
  
  
 
0.901
LOC102366049
Rho/rac guanine nucleotide exchange factor (GEF) 18b.
     
  0.577
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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