Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDRG4NDRG family member 4. (348 aa)    
Predicted Functional Partners:
NDRG1
N-myc downstream regulated 1.
    
   0.758
UBP1
Upstream binding protein 1.
      
 0.654
RBPMS2
RNA binding protein, mRNA processing factor 2.
    
 
 0.653
TOMM34
Translocase of outer mitochondrial membrane 34.
      
 0.650
LNX2
Ligand of numb-protein X 2.
    
 
 0.617
YWHAZ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
      
 0.570
DNAJB11
DnaJ heat shock protein family (Hsp40) member B11.
   
 
 0.564
GRHL2
Grainyhead like transcription factor 2.
      
 0.549
MAPT
Microtubule-associated protein.
   
 
 0.531
MYCN
MYCN proto-oncogene, bHLH transcription factor.
    
 
 0.495
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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