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STRINGSTRING
PHAX protein (Latimeria chalumnae) - STRING interaction network
"PHAX" - Phosphorylated adaptor for RNA export in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHAXPhosphorylated adaptor for RNA export (404 aa)    
Predicted Functional Partners:
HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (4101 aa)
       
      0.887
NUCKS1
Nuclear casein kinase and cyclin-dependent kinase substrate 1 (295 aa)
     
      0.881
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (147 aa)
     
 
  0.829
PIANP
PILR alpha associated neural protein (229 aa)
           
  0.821
NCBP1
Nuclear cap binding protein subunit 1, 80kDa (804 aa)
     
 
  0.819
KIF24
Uncharacterized protein; Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (1249 aa)
           
  0.780
SNUPN
Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs (360 aa)
     
   
  0.777
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (375 aa)
           
  0.768
SRRT
Serrate, RNA effector molecule (832 aa)
     
   
  0.766
NCBP2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5’ end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. The CBC complex is also involved in mediating U s [...] (164 aa)
     
 
  0.714
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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