STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Neuregulin 1. (409 aa)    
Predicted Functional Partners:
ERBB3
Protein kinase domain-containing protein.
    
 0.858
ERBB2
Receptor protein-tyrosine kinase.
    
 0.812
ERBB4
Protein kinase domain-containing protein.
    
 0.731
ERBB4-2
Protein kinase domain-containing protein.
    
 0.731
H3A7N7_LATCH
GF_recep_IV domain-containing protein.
    
 0.731
RNF41
Ring finger protein 41.
    
 0.595
RPS27A
Ribosomal protein S27a.
    
  0.590
BTC
EGF-like domain-containing protein.
     
 0.554
MEMO1
Mediator of cell motility 1.
   
  0.527
GAB1
GRB2 associated binding protein 1.
    
  0.522
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.