Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZUR5_LATCHUncharacterized protein. (276 aa)    
Predicted Functional Partners:
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
   
 
  0.914
CCNA2
Cyclin A2; Belongs to the cyclin family.
     
  0.900
LOC102367471
Uncharacterized protein; Belongs to the cyclin family.
     
  0.900
CCNE2
Cyclin E2; Belongs to the cyclin family.
     
  0.900
CCNE1
Cyclin E1; Belongs to the cyclin family.
     
  0.900
RBL2
RB transcriptional corepressor like 2.
     
  0.900
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
    
  0.900
RB1
Uncharacterized protein.
     
  0.900
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
    
  0.900
TFDP2
Transcription factor.
     
  0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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