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STRINGSTRING
ENSLACG00000001018 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000001018" - Poly [ADP-ribose] polymerase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLACG00000001018Poly [ADP-ribose] polymerase (601 aa)    
Predicted Functional Partners:
ENSLACG00000004350
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (103 aa)
     
 
  0.615
SPOP
Speckle-type POZ protein (374 aa)
     
 
  0.508
SPOPL
Speckle-type POZ protein-like b (392 aa)
     
 
  0.508
ENSLACG00000022479
annotation not available (222 aa)
     
      0.402
ENSLACG00000022300
annotation not available (114 aa)
     
      0.402
H3F3B
H3 histone, family 3A (136 aa)
     
      0.402
H3F3C
H3 histone, family 3C (109 aa)
     
      0.402
ENSLACG00000008380
annotation not available (129 aa)
     
      0.402
H3F3A
H3 histone, family 3A (136 aa)
     
      0.402
ENSLACG00000001795
Selenoprotein H (112 aa)
     
      0.402
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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