UCP2 protein (Latimeria chalumnae) - STRING interaction network

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UCP2

Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)

Predicted Functional Partners:

PPARG

0.613

GPAT4

0.590

ADORA1

0.587

SLC25A27

0.581

ACADM

0.577

PRDX3

0.574

MYOD1

0.568

CPT1B

0.563

RPA2

0.543

TBC1D9

0.542

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADM	PPARG	ENSLACP00000009742	ENSLACP00000010456	Acyl-CoA dehydrogenase medium chain.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.565
ACADM	UCP2	ENSLACP00000009742	ENSLACP00000001142	Acyl-CoA dehydrogenase medium chain.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.577
ADORA1	PPARG	ENSLACP00000015920	ENSLACP00000010456	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.571
ADORA1	UCP2	ENSLACP00000015920	ENSLACP00000001142	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.587
CPT1B	GPAT4	ENSLACP00000008053	ENSLACP00000004882	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	Glycerol-3-phosphate acyltransferase 4.	0.641
CPT1B	PPARG	ENSLACP00000008053	ENSLACP00000010456	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.670
CPT1B	UCP2	ENSLACP00000008053	ENSLACP00000001142	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.563
GPAT4	CPT1B	ENSLACP00000004882	ENSLACP00000008053	Glycerol-3-phosphate acyltransferase 4.	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	0.641
GPAT4	UCP2	ENSLACP00000004882	ENSLACP00000001142	Glycerol-3-phosphate acyltransferase 4.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.590
MYOD1	PPARG	ENSLACP00000016378	ENSLACP00000010456	Myogenic factor.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.473
MYOD1	UCP2	ENSLACP00000016378	ENSLACP00000001142	Myogenic factor.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.568
PPARG	ACADM	ENSLACP00000010456	ENSLACP00000009742	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Acyl-CoA dehydrogenase medium chain.	0.565
PPARG	ADORA1	ENSLACP00000010456	ENSLACP00000015920	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	0.571
PPARG	CPT1B	ENSLACP00000010456	ENSLACP00000008053	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	0.670
PPARG	MYOD1	ENSLACP00000010456	ENSLACP00000016378	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Myogenic factor.	0.473
PPARG	UCP2	ENSLACP00000010456	ENSLACP00000001142	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.613
PRDX3	UCP2	ENSLACP00000016627	ENSLACP00000001142	Peroxiredoxin 3.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.574
RPA2	UCP2	ENSLACP00000003064	ENSLACP00000001142	Replication protein A2.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.543
SLC25A27	UCP2	ENSLACP00000008972	ENSLACP00000001142	Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.581
TBC1D9	UCP2	ENSLACP00000001674	ENSLACP00000001142	TBC1 domain family member 9.	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.542