STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBASH3AUbiquitin associated and SH3 domain containing A. (590 aa)    
Predicted Functional Partners:
ZAP70
Tyrosine-protein kinase.
   
 0.728
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.596
CSTF3
Cleavage stimulation factor subunit 3.
     
 0.562
LCP2
Lymphocyte cytosolic protein 2.
   
 
 0.558
AIFM3
Apoptosis inducing factor mitochondria associated 3.
    
 
 0.556
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.540
H2ZY86_LATCH
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.511
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
  
 0.509
ENOPH1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
     
 0.505
CBLB
Cbl proto-oncogene B.
    
 
 0.499
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.