STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZUT7_LATCHTIR domain-containing protein. (1060 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.981
TLR8
Toll like receptor 8; Belongs to the Toll-like receptor family.
  
  
 
0.903
TLR7
Toll-like receptor 7.
  
  
 
0.900
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.843
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.752
TLR9
Toll-like receptor 9.
    
 0.667
EIF4H
Eukaryotic translation initiation factor 4H.
    
   0.635
IL6
Uncharacterized protein.
   
 
 0.598
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
    
 0.582
NHLRC2
NHL repeat containing 2.
    
 0.558
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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