Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTPROProtein tyrosine phosphatase receptor type O. (1222 aa)    
Predicted Functional Partners:
SCAI
Suppressor of cancer cell invasion.
      
 0.756
PTPRG
Protein tyrosine phosphatase receptor type G.
    
 0.609
NPHS2
NPHS2 stomatin family member, podocin.
   
 0.603
CHD1L
Chromodomain helicase DNA binding protein 1 like.
    
 
 0.591
H3AR28_LATCH
Uncharacterized protein.
   
  
 0.547
CDH5
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.524
RPL13A
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
    
  0.521
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.519
TLK2
Tousled like kinase 2.
    
 
 0.496
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.488
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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