STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INPP4BInositol polyphosphate-4-phosphatase type II B. (773 aa)    
Predicted Functional Partners:
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.954
INPP5B
Inositol polyphosphate-5-phosphatase B.
    
 0.931
IMPA2
Inositol-1-monophosphatase.
   
 
 0.927
LOC102366716
Inositol polyphosphate-5-phosphatase L.
     
 0.927
INPP5A
Inositol polyphosphate-5-phosphatase A.
     
 0.927
IMPA1
Inositol-1-monophosphatase.
   
 
 0.927
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 0.926
INPPL1
Inositol polyphosphate phosphatase like 1.
    
 0.925
LOC102351582
SH2 domain-containing protein.
    
 0.925
INPP1
Inositol polyphosphate-1-phosphatase.
     
 0.923
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.