STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102363060Tyrosine-protein kinase receptor. (1012 aa)    
Predicted Functional Partners:
PTN
Pleiotrophin.
    
 0.882
GRB2
Growth factor receptor bound protein 2.
    
 0.815
STAT3
Signal transducer and activator of transcription.
    
 0.710
GAB1
GRB2 associated binding protein 1.
    
 0.706
H2ZTT6_LATCH
Phosphoinositide phospholipase C.
    
 0.672
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.672
MDK
Midkine.
    
 0.652
SHC3
SHC adaptor protein 3.
    
 0.645
SHC1
SHC adaptor protein 1.
    
 0.645
FRS3
Fibroblast growth factor receptor substrate 3.
    
 0.622
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]