STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZUZ3_LATCHUncharacterized protein. (515 aa)    
Predicted Functional Partners:
LYPD6
LY6/PLAUR domain containing 6.
    
 0.702
CHRNB3
Cholinergic receptor nicotinic beta 3 subunit.
   
  0.686
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
   
  0.686
LYPD6B
LY6/PLAUR domain containing 6B.
    
 0.686
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
   
  0.658
APP
Amyloid beta precursor protein.
    
 
 0.650
RIC3
RIC3 acetylcholine receptor chaperone.
    
 
 0.639
CHRNA10
Cholinergic receptor nicotinic alpha 10 subunit.
   
  0.626
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
   
  0.626
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
   
  0.605
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.