VTCN1 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

VTCN1

V-set domain containing T cell activation inhibitor 1. (279 aa)

Predicted Functional Partners:

HELZ2

0.770

LOC102356960

0.588

NCCRP1

0.548

GZMK

0.547

GABRP

0.470

H3B4F2_LATCH

0.470

H3A3L8_LATCH

0.467

SUFU

0.467

NDUFAF2

0.467

PKHD1

0.467

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GABRP	VTCN1	ENSLACP00000013007	ENSLACP00000001217	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	V-set domain containing T cell activation inhibitor 1.	0.470
GZMK	NCCRP1	ENSLACP00000002446	ENSLACP00000020987	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish).	0.654
GZMK	VTCN1	ENSLACP00000002446	ENSLACP00000001217	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	V-set domain containing T cell activation inhibitor 1.	0.547
H3A3L8_LATCH	NDUFAF2	ENSLACP00000004239	ENSLACP00000013942	Uncharacterized protein.	NADH:ubiquinone oxidoreductase complex assembly factor 2.	0.593
H3A3L8_LATCH	PKHD1	ENSLACP00000004239	ENSLACP00000016644	Uncharacterized protein.	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	0.593
H3A3L8_LATCH	SUFU	ENSLACP00000004239	ENSLACP00000010491	Uncharacterized protein.	SUFU negative regulator of hedgehog signaling.	0.593
H3A3L8_LATCH	VTCN1	ENSLACP00000004239	ENSLACP00000001217	Uncharacterized protein.	V-set domain containing T cell activation inhibitor 1.	0.467
H3B4F2_LATCH	VTCN1	ENSLACP00000016773	ENSLACP00000001217	Gamma-aminobutyric acid (GABA) A receptor, zeta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	V-set domain containing T cell activation inhibitor 1.	0.470
HELZ2	VTCN1	ENSLACP00000009242	ENSLACP00000001217	Helicase with zinc finger 2.	V-set domain containing T cell activation inhibitor 1.	0.770
LOC102356960	VTCN1	ENSLACP00000008539	ENSLACP00000001217	Charged multivesicular body protein 3.	V-set domain containing T cell activation inhibitor 1.	0.588
NCCRP1	GZMK	ENSLACP00000020987	ENSLACP00000002446	Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish).	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.654
NCCRP1	VTCN1	ENSLACP00000020987	ENSLACP00000001217	Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish).	V-set domain containing T cell activation inhibitor 1.	0.548
NDUFAF2	H3A3L8_LATCH	ENSLACP00000013942	ENSLACP00000004239	NADH:ubiquinone oxidoreductase complex assembly factor 2.	Uncharacterized protein.	0.593
NDUFAF2	PKHD1	ENSLACP00000013942	ENSLACP00000016644	NADH:ubiquinone oxidoreductase complex assembly factor 2.	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	0.593
NDUFAF2	SUFU	ENSLACP00000013942	ENSLACP00000010491	NADH:ubiquinone oxidoreductase complex assembly factor 2.	SUFU negative regulator of hedgehog signaling.	0.593
NDUFAF2	VTCN1	ENSLACP00000013942	ENSLACP00000001217	NADH:ubiquinone oxidoreductase complex assembly factor 2.	V-set domain containing T cell activation inhibitor 1.	0.467
PKHD1	H3A3L8_LATCH	ENSLACP00000016644	ENSLACP00000004239	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	Uncharacterized protein.	0.593
PKHD1	NDUFAF2	ENSLACP00000016644	ENSLACP00000013942	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	NADH:ubiquinone oxidoreductase complex assembly factor 2.	0.593
PKHD1	SUFU	ENSLACP00000016644	ENSLACP00000010491	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	SUFU negative regulator of hedgehog signaling.	0.593
PKHD1	VTCN1	ENSLACP00000016644	ENSLACP00000001217	PKHD1 ciliary IPT domain containing fibrocystin/polyductin.	V-set domain containing T cell activation inhibitor 1.	0.467