Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZV00_LATCHProtein kinase domain-containing protein. (651 aa)    
Predicted Functional Partners:
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
    
 0.592
NEK2
NIMA related kinase 2.
   
 
 0.587
ME3
Malic enzyme.
    
  0.582
H2ZSE1_LATCH
Uncharacterized protein.
   
  
 0.561
TCTEX1D2
Tctex1 domain containing 2.
    
 
 0.524
H3A0V9_LATCH
DUF5595 domain-containing protein.
   
  
 0.522
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
     
 0.505
CFAP410
Cilia and flagella associated protein 410.
    
 
 0.503
ME2
Malic enzyme.
    
  0.493
H3ASX0_LATCH
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.491
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]