Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VIL1Villin 1. (832 aa)    
Predicted Functional Partners:
KNG1
Uncharacterized protein.
      
 0.654
COG8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.634
COG3
Component of oligomeric golgi complex 3.
    
 
 0.628
COG4
Component of oligomeric golgi complex 4.
    
 
 0.605
C8G
Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.553
C8A
Complement C8 alpha chain.
      
 0.547
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.534
COG6-2
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.534
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.530
TWF1
Twinfilin actin binding protein 1.
    
 0.511
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (38%) [HD]