H2ZV13_LATCH protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

H2ZV13_LATCH

Uncharacterized protein. (138 aa)

Predicted Functional Partners:

SUPT16H

0.938

IWS1

0.938

SSRP1

0.932

SUPT5H

0.891

POLR2C

0.878

SUPT4H1

0.877

POLR2B

0.870

POLR2E

0.867

CDC73

0.861

SETD2

0.853

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	H2ZV13_LATCH	ENSLACP00000001436	ENSLACP00000001234	Cell division cycle 73.	Uncharacterized protein.	0.861
CDC73	IWS1	ENSLACP00000001436	ENSLACP00000017266	Cell division cycle 73.	Interacts with SUPT6H, CTD assembly factor 1.	0.733
CDC73	POLR2B	ENSLACP00000001436	ENSLACP00000003304	Cell division cycle 73.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.930
CDC73	POLR2C	ENSLACP00000001436	ENSLACP00000004165	Cell division cycle 73.	RNA polymerase II subunit C.	0.858
CDC73	POLR2E	ENSLACP00000001436	ENSLACP00000015549	Cell division cycle 73.	RNA polymerase II subunit E.	0.980
CDC73	SETD2	ENSLACP00000001436	ENSLACP00000008064	Cell division cycle 73.	SET domain containing 2, histone lysine methyltransferase.	0.906
CDC73	SSRP1	ENSLACP00000001436	ENSLACP00000003964	Cell division cycle 73.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.976
CDC73	SUPT16H	ENSLACP00000001436	ENSLACP00000004800	Cell division cycle 73.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.980
CDC73	SUPT4H1	ENSLACP00000001436	ENSLACP00000018584	Cell division cycle 73.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.977
CDC73	SUPT5H	ENSLACP00000001436	ENSLACP00000009824	Cell division cycle 73.	Transcription elongation factor SPT5.	0.975
H2ZV13_LATCH	CDC73	ENSLACP00000001234	ENSLACP00000001436	Uncharacterized protein.	Cell division cycle 73.	0.861
H2ZV13_LATCH	IWS1	ENSLACP00000001234	ENSLACP00000017266	Uncharacterized protein.	Interacts with SUPT6H, CTD assembly factor 1.	0.938
H2ZV13_LATCH	POLR2B	ENSLACP00000001234	ENSLACP00000003304	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.870
H2ZV13_LATCH	POLR2C	ENSLACP00000001234	ENSLACP00000004165	Uncharacterized protein.	RNA polymerase II subunit C.	0.878
H2ZV13_LATCH	POLR2E	ENSLACP00000001234	ENSLACP00000015549	Uncharacterized protein.	RNA polymerase II subunit E.	0.867
H2ZV13_LATCH	SETD2	ENSLACP00000001234	ENSLACP00000008064	Uncharacterized protein.	SET domain containing 2, histone lysine methyltransferase.	0.853
H2ZV13_LATCH	SSRP1	ENSLACP00000001234	ENSLACP00000003964	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.932
H2ZV13_LATCH	SUPT16H	ENSLACP00000001234	ENSLACP00000004800	Uncharacterized protein.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.938
H2ZV13_LATCH	SUPT4H1	ENSLACP00000001234	ENSLACP00000018584	Uncharacterized protein.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.877
H2ZV13_LATCH	SUPT5H	ENSLACP00000001234	ENSLACP00000009824	Uncharacterized protein.	Transcription elongation factor SPT5.	0.891