ASPDH protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ASPDH

Aspartate dehydrogenase domain containing. (285 aa)

Predicted Functional Partners:

GOT2

0.838

GOT1L1

0.838

ASS1

0.805

LOC102367420

0.800

ASPA

0.800

ASRGL1

0.800

ADSS1

0.800

NAT8L

0.800

CAD

0.800

LOC102345276

0.800

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSS1	ASPA	ENSLACP00000002379	ENSLACP00000000607	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Aspartoacylase.	0.901
ADSS1	ASPDH	ENSLACP00000002379	ENSLACP00000001246	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Aspartate dehydrogenase domain containing.	0.800
ADSS1	ASRGL1	ENSLACP00000002379	ENSLACP00000001710	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Asparaginase and isoaspartyl peptidase 1.	0.905
ADSS1	ASS1	ENSLACP00000002379	ENSLACP00000020235	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Argininosuccinate synthase 1.	0.948
ADSS1	CAD	ENSLACP00000002379	ENSLACP00000013150	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.945
ADSS1	GOT1L1	ENSLACP00000002379	ENSLACP00000023621	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Glutamic-oxaloacetic transaminase 1 like 1.	0.925
ADSS1	GOT2	ENSLACP00000002379	ENSLACP00000001398	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Aspartate aminotransferase.	0.926
ADSS1	LOC102345276	ENSLACP00000002379	ENSLACP00000019962	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.964
ADSS1	LOC102367420	ENSLACP00000002379	ENSLACP00000000524	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Amine oxidase.	0.901
ADSS1	NAT8L	ENSLACP00000002379	ENSLACP00000005191	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	N-acetyltransferase 8 like.	0.900
ASPA	ADSS1	ENSLACP00000000607	ENSLACP00000002379	Aspartoacylase.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.901
ASPA	ASPDH	ENSLACP00000000607	ENSLACP00000001246	Aspartoacylase.	Aspartate dehydrogenase domain containing.	0.800
ASPA	ASRGL1	ENSLACP00000000607	ENSLACP00000001710	Aspartoacylase.	Asparaginase and isoaspartyl peptidase 1.	0.903
ASPA	ASS1	ENSLACP00000000607	ENSLACP00000020235	Aspartoacylase.	Argininosuccinate synthase 1.	0.901
ASPA	CAD	ENSLACP00000000607	ENSLACP00000013150	Aspartoacylase.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.900
ASPA	GOT1L1	ENSLACP00000000607	ENSLACP00000023621	Aspartoacylase.	Glutamic-oxaloacetic transaminase 1 like 1.	0.901
ASPA	GOT2	ENSLACP00000000607	ENSLACP00000001398	Aspartoacylase.	Aspartate aminotransferase.	0.900
ASPA	LOC102345276	ENSLACP00000000607	ENSLACP00000019962	Aspartoacylase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.901
ASPA	LOC102367420	ENSLACP00000000607	ENSLACP00000000524	Aspartoacylase.	Amine oxidase.	0.903
ASPA	NAT8L	ENSLACP00000000607	ENSLACP00000005191	Aspartoacylase.	N-acetyltransferase 8 like.	0.946