Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STIM2Stromal interaction molecule 2. (639 aa)    
Predicted Functional Partners:
STIM1
Stromal interaction molecule 1.
  
 
0.997
ORAI1
ORAI calcium release-activated calcium modulator 1.
    
 0.997
ORAI3
Uncharacterized protein.
    
 0.995
LOC102346192
Uncharacterized protein.
    
 0.990
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.973
PRKAA2
Non-specific serine/threonine protein kinase.
    
   0.961
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
   0.956
PRKAA1
Non-specific serine/threonine protein kinase.
    
   0.933
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
    
   0.890
SARAF
Store-operated calcium entry associated regulatory factor.
    
 
 0.776
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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