RHOT2 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RHOT2

Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (589 aa)

Predicted Functional Partners:

WDR90

0.959

ITSN2

0.844

WDR24

0.763

EGFL6

0.750

ANKS3

0.736

H3AJ45_LATCH

0.734

ITSN1

0.734

RHBDL1

0.732

ARHGAP6

0.728

COG3

0.726

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKS3	ARHGAP6	ENSLACP00000001794	ENSLACP00000016241	Ankyrin repeat and sterile alpha motif domain containing 3.	Rho GTPase activating protein 6.	0.691
ANKS3	COG3	ENSLACP00000001794	ENSLACP00000007143	Ankyrin repeat and sterile alpha motif domain containing 3.	Component of oligomeric golgi complex 3.	0.719
ANKS3	EGFL6	ENSLACP00000001794	ENSLACP00000016533	Ankyrin repeat and sterile alpha motif domain containing 3.	EGF like domain multiple 6.	0.752
ANKS3	RHBDL1	ENSLACP00000001794	ENSLACP00000010575	Ankyrin repeat and sterile alpha motif domain containing 3.	Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.715
ANKS3	RHOT2	ENSLACP00000001794	ENSLACP00000001250	Ankyrin repeat and sterile alpha motif domain containing 3.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.736
ANKS3	WDR24	ENSLACP00000001794	ENSLACP00000018033	Ankyrin repeat and sterile alpha motif domain containing 3.	WD repeat domain 24.	0.752
ANKS3	WDR90	ENSLACP00000001794	ENSLACP00000002441	Ankyrin repeat and sterile alpha motif domain containing 3.	WD repeat domain 90.	0.833
ARHGAP6	ANKS3	ENSLACP00000016241	ENSLACP00000001794	Rho GTPase activating protein 6.	Ankyrin repeat and sterile alpha motif domain containing 3.	0.691
ARHGAP6	COG3	ENSLACP00000016241	ENSLACP00000007143	Rho GTPase activating protein 6.	Component of oligomeric golgi complex 3.	0.689
ARHGAP6	EGFL6	ENSLACP00000016241	ENSLACP00000016533	Rho GTPase activating protein 6.	EGF like domain multiple 6.	0.720
ARHGAP6	RHBDL1	ENSLACP00000016241	ENSLACP00000010575	Rho GTPase activating protein 6.	Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.701
ARHGAP6	RHOT2	ENSLACP00000016241	ENSLACP00000001250	Rho GTPase activating protein 6.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.728
ARHGAP6	WDR24	ENSLACP00000016241	ENSLACP00000018033	Rho GTPase activating protein 6.	WD repeat domain 24.	0.682
ARHGAP6	WDR90	ENSLACP00000016241	ENSLACP00000002441	Rho GTPase activating protein 6.	WD repeat domain 90.	0.684
COG3	ANKS3	ENSLACP00000007143	ENSLACP00000001794	Component of oligomeric golgi complex 3.	Ankyrin repeat and sterile alpha motif domain containing 3.	0.719
COG3	ARHGAP6	ENSLACP00000007143	ENSLACP00000016241	Component of oligomeric golgi complex 3.	Rho GTPase activating protein 6.	0.689
COG3	EGFL6	ENSLACP00000007143	ENSLACP00000016533	Component of oligomeric golgi complex 3.	EGF like domain multiple 6.	0.697
COG3	RHBDL1	ENSLACP00000007143	ENSLACP00000010575	Component of oligomeric golgi complex 3.	Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.692
COG3	RHOT2	ENSLACP00000007143	ENSLACP00000001250	Component of oligomeric golgi complex 3.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.726
COG3	WDR24	ENSLACP00000007143	ENSLACP00000018033	Component of oligomeric golgi complex 3.	WD repeat domain 24.	0.705