Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin A2; Belongs to the cyclin family. (447 aa)    
Predicted Functional Partners:
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.999
RB1
Uncharacterized protein.
   
 0.999
E2F1
E2F transcription factor 1.
   
 0.999
LOC102367189
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.999
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.999
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.999
CCNA1
Cyclin A1; Belongs to the cyclin family.
  
 
0.996
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.995
H3ATF5_LATCH
Cdc6_C domain-containing protein.
   
 0.995
SKP2
S-phase kinase associated protein 2.
   
 0.995
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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