Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CACHD1Cache domain containing 1. (1137 aa)    
Predicted Functional Partners:
TMEM259
Transmembrane protein 259.
      
 0.924
EMC1
ER membrane protein complex subunit 1.
      
 0.794
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A.
      
 0.774
GGCX
Gamma-glutamyl carboxylase.
      
 0.771
LOC102358736
Sphingomyelin phosphodiesterase, acid-like 3B.
      
 0.755
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
    
  0.725
CACNB4
Calcium channel, voltage-dependent, beta 4a subunit.
   
 0.699
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
 0.699
CACNB2
Calcium voltage-gated channel auxiliary subunit beta 2.
   
 0.699
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
   
 0.699
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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