STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HTR2A5-hydroxytryptamine receptor 2A. (469 aa)    
Predicted Functional Partners:
HTR2C
5-hydroxytryptamine receptor 2C; Belongs to the G-protein coupled receptor 1 family.
    
0.979
HTR2B
5-hydroxytryptamine receptor 2B.
  
 
0.970
LOC102359416
Uncharacterized protein.
    
 0.956
GRM2
Glutamate metabotropic receptor 2.
    
 0.732
REEP3
Receptor expression-enhancing protein.
      
 0.700
DACT2
Dishevelled-binding antagonist of beta-catenin 2.
      
 0.603
GNA11
G protein subunit alpha 11.
    
 0.582
TPH1
Tryptophan hydroxylase 1.
      
 0.554
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.553
GNAS
GNAS complex locus.
    
 0.553
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.