STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USF1Upstream transcription factor 1. (293 aa)    
Predicted Functional Partners:
USF2
Upstream transcription factor 2, c-fos interacting.
   
 0.997
GTF2I
General transcription factor IIi.
    
 
 0.970
FOSL1
FOS like 1, AP-1 transcription factor subunit.
    
 
 0.820
LOC102352539
Uncharacterized protein.
    
 0.785
SP1
Sp1 transcription factor.
    
 0.764
GLI3
GLI family zinc finger 3.
    
 0.743
MAPK14
Mitogen-activated protein kinase.
    
 0.727
MAPK11
Mitogen-activated protein kinase.
    
 0.727
CTCF
CCCTC-binding factor.
    
 0.716
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 
 0.708
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.