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DIRAS1 protein (Latimeria chalumnae) - STRING interaction network
"DIRAS1" - DIRAS family, GTP-binding RAS-like 1b in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family, GTP-binding RAS-like 1b (198 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family (1077 aa)
       
      0.740
MED16
Mediator complex subunit 16 (834 aa)
           
  0.708
GRIN3B
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family (907 aa)
     
 
  0.699
TMEM259
Transmembrane protein 259 (583 aa)
           
  0.688
PTBP1
Polypyrimidine tract binding protein 1 (560 aa)
       
 
  0.603
ARID3A
AT rich interactive domain 3A (BRIGHT-like) (554 aa)
       
 
  0.600
WDR18
WD repeat domain 18 (431 aa)
     
 
  0.595
GADD45B
Growth arrest and DNA-damage-inducible, beta (158 aa)
           
  0.545
PLPPR3
Lipid phosphate phosphatase-related protein type 3a (712 aa)
     
 
  0.525
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4 (750 aa)
     
 
  0.513
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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