STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.804
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.692
LOC102351219
Rap guanine nucleotide exchange factor (GEF) 3.
   
 0.687
LRRC17
Leucine rich repeat containing 17.
    
 0.676
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.670
NKX1-1
NK1 homeobox 1.
     
 0.642
LCAT
Lecithin-cholesterol acyltransferase.
      
 0.641
CREB3L1
cAMP responsive element binding protein 3 like 1.
      
 0.635
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.604
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.604
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.