Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TTBK2Tau tubulin kinase 2. (1233 aa)    
Predicted Functional Partners:
CEP164
Centrosomal protein 164.
    
 0.976
CEP89
Centrosomal protein 89.
     
 0.898
FBF1
Fas binding factor 1.
      
 0.891
IFT140
Intraflagellar transport 140.
      
 0.844
IFT88
Intraflagellar transport 88.
    
 
 0.839
CEP19
Centrosomal protein 19.
      
 0.828
CEP350
Centrosomal protein 350.
   
 
 0.815
H2ZTF5_LATCH
SCA7 domain-containing protein.
    
 
 0.813
LRRC45
Leucine rich repeat containing 45.
   
 
 0.813
FAM83E
Family with sequence similarity 83 member E.
    
 0.801
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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