STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF33DH domain-containing protein. (800 aa)    
Predicted Functional Partners:
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
      
 0.846
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.776
ARHGEF19
Rho guanine nucleotide exchange factor 19.
    
 0.753
PLEKHG4B
Pleckstrin homology and RhoGEF domain containing G4B.
     
 0.745
H3AJJ8_LATCH
Rho guanine nucleotide exchange factor (GEF) 15.
    
 0.718
FGD3
FYVE, RhoGEF and PH domain containing 3.
     
 0.715
ARHGEF10
Rho guanine nucleotide exchange factor 10.
     
 0.712
RASGRF2
Ras protein specific guanine nucleotide releasing factor 2.
     
 0.707
TRIO
Trio Rho guanine nucleotide exchange factor.
     
 0.674
SPEG
Ig-like domain-containing protein.
     
 0.670
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.