STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF33DH domain-containing protein. (800 aa)    
Predicted Functional Partners:
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.759
ARHGEF19
Rho guanine nucleotide exchange factor 19.
    
 0.713
PLEKHG4B
Pleckstrin homology and RhoGEF domain containing G4B.
     
 0.711
H3AJJ8_LATCH
Rho guanine nucleotide exchange factor (GEF) 15.
    
 0.697
FGD3
FYVE, RhoGEF and PH domain containing 3.
     
 0.685
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
      
 0.672
RASGRF2
Ras protein specific guanine nucleotide releasing factor 2.
     
 0.605
ARHGEF10
Rho guanine nucleotide exchange factor 10.
      
0.521
LOC102356032
Fleer.
      
 0.475
TRIO
Trio Rho guanine nucleotide exchange factor.
   
 
 0.443
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.