STRINGSTRING
ST8SIA4 protein (Latimeria chalumnae) - STRING interaction network
"ST8SIA4" - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (291 aa)    
Predicted Functional Partners:
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (188 aa)
           
  0.594
NCAM1
Neural cell adhesion molecule 1 (1111 aa)
     
  0.593
STX2
Syntaxin 2 (277 aa)
     
   
  0.573
LMAN1
Lectin, mannose-binding, 1 (332 aa)
           
  0.543
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (301 aa)
           
  0.535
STX1A
Syntaxin 1A (brain) (290 aa)
     
   
  0.440
STX1B
Syntaxin 1B (283 aa)
     
   
  0.440
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] (341 aa)
           
  0.430
LRIT2
Leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 (1185 aa)
     
    0.415
LRIT3
Leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 (651 aa)
     
    0.415
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (12%) [HD]