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HAAO protein (Latimeria chalumnae) - STRING interaction network
"HAAO" - 3-hydroxyanthranilate 3,4-dioxygenase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAAO3-hydroxyanthranilate 3,4-dioxygenase (252 aa)    
Predicted Functional Partners:
KYNU
Uncharacterized protein; Kynureninase (278 aa)
   
 
  0.995
KMO
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (474 aa)
   
   
  0.955
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide (521 aa)
     
 
  0.912
PAH
Phenylalanine hydroxylase (335 aa)
     
   
  0.803
TDO2
Tryptophan 2,3-dioxygenase (307 aa)
     
   
  0.799
QPRT
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA); Belongs to the NadC/ModD family (324 aa)
     
   
  0.798
HGD
Homogentisate 1,2-dioxygenase (459 aa)
     
   
  0.789
NAPRT
Nicotinate phosphoribosyltransferase (581 aa)
     
 
  0.751
FAH
Fumarylacetoacetate hydrolase (fumarylacetoacetase) (348 aa)
     
   
  0.705
TTC36
Tetratricopeptide repeat domain 36 (216 aa)
     
        0.678
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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