Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2ZV93_LATCH14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (117 aa)    
Predicted Functional Partners:
CDC25C
Cell division cycle 25C.
    
 0.964
TSC2
TSC complex subunit 2.
    
 0.798
CTNNB1
Catenin beta 1.
   
 0.749
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.719
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.719
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.719
YWHAG
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.
   
  0.687
YWHAH
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family.
   
  0.687
WWTR1
WW domain containing transcription regulator 1.
    
 0.686
YAP1
Yes associated protein 1.
    
 0.686
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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