STRINGSTRING
RNF5 protein (Latimeria chalumnae) - STRING interaction network
"RNF5" - Ring finger protein 5, E3 ubiquitin protein ligase in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF5Ring finger protein 5, E3 ubiquitin protein ligase (132 aa)    
Predicted Functional Partners:
RNF185
Ring finger protein 185 (195 aa)
         
 
0.841
UBA52
Uncharacterized protein (128 aa)
     
    0.619
DERL1
Derlin 1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (254 aa)
     
  0.606
KXD1
Ubiquitin A-52 residue ribosomal protein fusion product 1 (231 aa)
     
    0.526
DERL2
Derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (239 aa)
     
  0.493
DERL3
Derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (203 aa)
     
  0.493
CFTR
Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); Involved in the transport of chloride ions (1491 aa)
       
  0.459
ERLIN2
ER lipid raft associated 2 (338 aa)
     
  0.434
ERLIN1
ER lipid raft associated 1 (328 aa)
     
  0.434
ERLEC1
Endoplasmic reticulum lectin 1 (486 aa)
     
 
  0.416
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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