• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
RNF5 protein (Latimeria chalumnae) - STRING interaction network
"RNF5" - Ring finger protein 5, E3 ubiquitin protein ligase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF5Ring finger protein 5, E3 ubiquitin protein ligase (132 aa)    
Predicted Functional Partners:
RNF185
Ring finger protein 185 (195 aa)
     
0.820
AMFR
Autocrine motility factor receptor (653 aa)
     
 
  0.812
UBE2E3
Ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family (153 aa)
     
 
  0.770
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes (356 aa)
     
 
  0.735
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (254 aa)
     
 
  0.700
PEX2
Peroxisomal biogenesis factor 2 (299 aa)
     
 
  0.689
JKAMP
JNK1/MAPK8-associated membrane protein (321 aa)
       
 
  0.654
UBE2J1
Ubiquitin-conjugating enzyme E2, J1; Belongs to the ubiquitin-conjugating enzyme family (321 aa)
       
 
  0.636
UBE2E1
annotation not available (193 aa)
     
 
  0.623
RNF26
Ring finger protein 26 (451 aa)
     
   
  0.614
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
Server load: low (13%) [HD]