Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTCHD1Patched domain containing 1. (902 aa)    
Predicted Functional Partners:
FICD
FIC domain containing.
      
 0.786
RIPK4
Receptor interacting serine/threonine kinase 4.
    
 
 0.751
NWD2
NACHT and WD repeat domain containing 2.
      
 0.731
PLAGL2
PLAG1 like zinc finger 2.
      
 0.686
ENC1
Ectodermal-neural cortex 1.
      
 0.685
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.678
VPS26B
VPS26, retromer complex component B.
    
 
 0.668
GPR85
G protein-coupled receptor 85.
      
 0.659
DLGAP2
DLG associated protein 2.
   
  
 0.644
SHANK2
SH3 and multiple ankyrin repeat domains 2.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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