Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIFM1Apoptosis inducing factor mitochondria associated 1. (625 aa)    
Predicted Functional Partners:
CHCHD4
Coiled-coil-helix-coiled-coil-helix domain containing 4.
    
 
 0.966
NDUFS5
NADH:ubiquinone oxidoreductase subunit S5.
    
 
 0.946
AK2
Adenylate kinase 2; Belongs to the adenylate kinase family.
   
 
 0.930
LOC102347712
Thioredoxin; Belongs to the thioredoxin family.
   
 
 0.921
BAX
Uncharacterized protein.
    
 0.918
LOC102359041
Zgc:153993.
    
 0.916
MACROH2A1
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
  
 0.912
MACROH2A2
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
  
 0.912
H3B8N0_LATCH
Histone H2A; Belongs to the histone H2A family.
    
  0.905
H2AX
Histone H2A; Belongs to the histone H2A family.
    
  0.905
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.