STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX1Deltex E3 ubiquitin ligase 1. (322 aa)    
Predicted Functional Partners:
LOC102357987
Uncharacterized protein.
    
 0.974
NOTCH1
Notch receptor 1.
    
 0.974
NOTCH3
Notch receptor 3.
    
 0.954
NOTCH2
Notch receptor 2.
    
 0.938
ITCH
E3 ubiquitin-protein ligase.
    
 0.827
WWP1
E3 ubiquitin-protein ligase.
    
 0.777
WWP2
E3 ubiquitin-protein ligase.
    
 0.777
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.738
RPS27A
Ribosomal protein S27a.
    
  0.600
DVL1
Dishevelled segment polarity protein 1.
    
 0.575
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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