Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRRC2AProline rich coiled-coil 2A. (1714 aa)    
Predicted Functional Partners:
YTHDF1
YTH N6-methyladenosine RNA binding protein 1.
    
 
 0.818
GPANK1
G-patch domain and ankyrin repeats 1.
      
 0.792
EIF3A
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
   0.778
YTHDC2
YTH domain containing 2.
   
 
 0.753
FMR1
Fragile X mental retardation 1.
   
 
 0.735
YTHDF3
YTH N6-methyladenosine RNA binding protein 3.
   
 
 0.700
ANKRD17
Ankyrin repeat domain 17.
   
 
 0.698
UBAP2L
Ubiquitin associated protein 2 like.
   
 
 0.694
YTHDC1
YTH domain containing 1.
   
 
 0.694
UBAP2
Ubiquitin associated protein 2.
   
 
 0.694
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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