STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZVF6_LATCHIg-like domain-containing protein; Belongs to the MHC class I family. (226 aa)    
Predicted Functional Partners:
RPA2
Replication protein A2.
   
 0.919
PDIA3
Protein disulfide-isomerase.
    
 0.887
CALR3
Calreticulin.
    
 0.836
LOC106706091
Uncharacterized protein.
    
  0.827
H3AVH0_LATCH
Uncharacterized protein.
    
  0.760
H2ZWA0_LATCH
Uncharacterized protein.
   
 0.696
STN1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
   
 0.696
SASS6
SAS-6 centriolar assembly protein.
   
 0.696
H3AJ79_LATCH
Ig-like domain-containing protein.
     
  0.680
TAPBP
Uncharacterized protein.
 
 
 0.675
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.