STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB8Integrin beta; Belongs to the integrin beta chain family. (637 aa)    
Predicted Functional Partners:
ITGAV
Integrin_alpha2 domain-containing protein.
    
 0.999
VTN
Vitronectin b.
    
 0.978
PARVA
Parvin alpha.
   
 0.955
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.951
SRC
Tyrosine-protein kinase.
    
 0.935
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
    
 0.925
LAMC2
Uncharacterized protein.
    
 0.925
LAMC1
Laminin subunit gamma 1.
    
 0.920
LAMC3
Laminin subunit gamma 3.
    
 0.920
LAMB1
Laminin subunit beta 1.
    
 0.919
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.