Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZVF8_LATCHUncharacterized protein. (313 aa)    
Predicted Functional Partners:
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.913
LOC102352712
Protein tyrosine phosphatase non-receptor type 11b.
    
 0.913
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.899
SKAP2
Src kinase associated phosphoprotein 2.
   
 
 0.579
GRB2
Growth factor receptor bound protein 2.
   
  0.575
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.560
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.560
ARMC3
Armadillo repeat containing 3.
    
 
 0.497
LOC102366592
Cytidine monophospho-N-acetylneuraminic acid hydroxylase.
      
 0.468
TRIM3
Tripartite motif containing 3.
    
 0.460
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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