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CDKN2B protein (Latimeria chalumnae) - STRING interaction network
"CDKN2B" - Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4) in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
CDKN2BCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4) (128 aa)    
Predicted Functional Partners:
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily (306 aa)
     
  0.986
ENSLACG00000012491
Cyclin-dependent kinase 21; Si-dkeyp-57f11.1; Belongs to the protein kinase superfamily (327 aa)
     
  0.966
CDK6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily (322 aa)
     
  0.966
CCND1
Cyclin D1; Belongs to the cyclin family (292 aa)
     
  0.931
MYC
MYC proto-oncogene, bHLH transcription factor; V-myc avian myelocytomatosis viral oncogene homolog (412 aa)
       
  0.916
ENSLACG00000018920
Myelocytomatosis oncogene homolog (434 aa)
       
  0.902
CCND3
Cyclin D3; Belongs to the cyclin family (292 aa)
       
  0.865
ORC5
Uncharacterized protein; Origin recognition complex, subunit 5 (264 aa)
     
      0.783
CDKN1A
Uncharacterized protein; Cyclin-dependent kinase inhibitor 1A (p21, Cip1) (171 aa)
     
   
  0.783
TMCO1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling (188 aa)
     
   
  0.771
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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