Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)    
Predicted Functional Partners:
SMPD4
Sphingomyelin phosphodiesterase 4.
     
 0.983
SMPD2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.979
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.928
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.925
SMPD1
Sphingomyelin phosphodiesterase 1.
     
 0.924
SGMS1
Sphingomyelin synthase 1.
     
 0.924
H3BCB4_LATCH
PAP2_C domain-containing protein.
     
 0.924
SGPP1
Sphingosine-1-phosphate phosphatase 1.
     
 0.924
GALC
Galactosylceramidase.
     
 0.924
SGMS2
Sphingomyelin synthase 2.
     
 0.924
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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