Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BBS12Bardet-Biedl syndrome 12. (709 aa)    
Predicted Functional Partners:
MKKS
McKusick-Kaufman syndrome.
    
 0.994
BBS10
Bardet-Biedl syndrome 10.
    
 0.989
BBS7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.986
BBS9
Bardet-Biedl syndrome 9.
    
 0.926
BBS2
Bardet-Biedl syndrome 2 protein homolog.
    
 0.909
H3A6Z7_LATCH
Bardet-Biedl syndrome 1.
    
 0.887
CCT8
Chaperonin containing TCP1 subunit 8.
    
 0.874
LOC102367489
Uncharacterized protein.
    
 0.848
TCP1
T-complex 1.
    
 0.848
BBS4
Bardet-Biedl syndrome 4.
    
 0.830
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.