Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
POLLDNA polymerase lambda; Belongs to the DNA polymerase type-X family. (572 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.978
XRCC5
X-ray repair cross complementing 5.
    
 0.957
XRCC6
X-ray repair cross complementing 6.
    
 0.955
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.953
LIG4
DNA ligase.
  
 0.923
H3AC16_LATCH
X-ray repair complementing defective repair in Chinese hamster cells 1.
    
 0.908
WDR11
WD repeat domain 11.
      
 0.893
PNKP
Polynucleotide kinase 3'-phosphatase.
    
 0.869
DCLRE1C
DNA cross-link repair 1C.
  
 
 0.865
H3ALV1_LATCH
Uncharacterized protein.
  
 0.843
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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