Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GOT2Aspartate aminotransferase. (392 aa)    
Predicted Functional Partners:
MDH2
Malate dehydrogenase.
   
 0.999
GLUD1
Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.989
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.989
LDHA
L-lactate dehydrogenase.
   
 0.989
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 0.988
LOC102361787
Aminotran_1_2 domain-containing protein.
   
 0.987
H2ZXP4_LATCH
Uncharacterized protein.
   
 0.987
MDH1
Malate dehydrogenase.
   
 0.986
FH
Fumarate hydratase.
   
 0.980
LOC102363309
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.975
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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