STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102354262Mitogen-activated protein kinase. (330 aa)    
Predicted Functional Partners:
LOC102365238
Ribosomal protein S6 kinase.
   
0.986
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.984
MAP2K2
Mitogen-activated protein kinase kinase 2a.
   
0.984
PTPN7
Protein tyrosine phosphatase non-receptor type 7.
    
 0.984
PTPRR
Protein tyrosine phosphatase receptor type R.
    
 0.980
PLA2G4A
Phospholipase A2.
    
 0.979
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.979
DUSP3
Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
 0.975
CEBPB
CCAAT/enhancer-binding protein.
    
 0.972
RPS6KA3
Ribosomal protein S6 kinase A3.
   
0.971
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.