Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SENP8SUMO peptidase family member, NEDD8 specific. (212 aa)    
Predicted Functional Partners:
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.999
CUL1
Cullin 1; Belongs to the cullin family.
    
 
 0.943
UCHL3
Ubiquitin carboxyl-terminal hydrolase.
    
 0.886
UCHL1
Ubiquitin carboxyl-terminal hydrolase.
    
 0.886
ACO1
Aconitase 1.
  
 
 0.854
IREB2
Iron responsive element binding protein 2.
  
 
 0.854
ACO2
Aconitase 2.
  
 
 0.854
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
    
 0.850
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
    
   0.814
OTUD5
OTU deubiquitinase 5.
      
 0.791
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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