SENP8 protein (Latimeria chalumnae) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

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Score

SENP8

SUMO peptidase family member, NEDD8 specific. (212 aa)

Predicted Functional Partners:

NEDD8

0.999

PIGL

0.942

ACO1

0.937

IREB2

0.937

ACO2

0.937

UBA3

0.910

UCHL1

0.883

UCHL3

0.882

NAE1

0.843

CS

0.811

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACO1	CS	ENSLACP00000001046	ENSLACP00000021587	Aconitase 1.	Citrate synthase; Belongs to the citrate synthase family.	0.975
ACO1	IREB2	ENSLACP00000001046	ENSLACP00000001317	Aconitase 1.	Iron responsive element binding protein 2.	0.578
ACO1	NEDD8	ENSLACP00000001046	ENSLACP00000006393	Aconitase 1.	NEDD8 ubiquitin like modifier.	0.644
ACO1	SENP8	ENSLACP00000001046	ENSLACP00000001417	Aconitase 1.	SUMO peptidase family member, NEDD8 specific.	0.937
ACO2	CS	ENSLACP00000013466	ENSLACP00000021587	Aconitase 2.	Citrate synthase; Belongs to the citrate synthase family.	0.995
ACO2	SENP8	ENSLACP00000013466	ENSLACP00000001417	Aconitase 2.	SUMO peptidase family member, NEDD8 specific.	0.937
CS	ACO1	ENSLACP00000021587	ENSLACP00000001046	Citrate synthase; Belongs to the citrate synthase family.	Aconitase 1.	0.975
CS	ACO2	ENSLACP00000021587	ENSLACP00000013466	Citrate synthase; Belongs to the citrate synthase family.	Aconitase 2.	0.995
CS	IREB2	ENSLACP00000021587	ENSLACP00000001317	Citrate synthase; Belongs to the citrate synthase family.	Iron responsive element binding protein 2.	0.974
CS	SENP8	ENSLACP00000021587	ENSLACP00000001417	Citrate synthase; Belongs to the citrate synthase family.	SUMO peptidase family member, NEDD8 specific.	0.811
IREB2	ACO1	ENSLACP00000001317	ENSLACP00000001046	Iron responsive element binding protein 2.	Aconitase 1.	0.578
IREB2	CS	ENSLACP00000001317	ENSLACP00000021587	Iron responsive element binding protein 2.	Citrate synthase; Belongs to the citrate synthase family.	0.974
IREB2	NEDD8	ENSLACP00000001317	ENSLACP00000006393	Iron responsive element binding protein 2.	NEDD8 ubiquitin like modifier.	0.644
IREB2	SENP8	ENSLACP00000001317	ENSLACP00000001417	Iron responsive element binding protein 2.	SUMO peptidase family member, NEDD8 specific.	0.937
NAE1	NEDD8	ENSLACP00000011007	ENSLACP00000006393	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	NEDD8 ubiquitin like modifier.	0.990
NAE1	SENP8	ENSLACP00000011007	ENSLACP00000001417	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO peptidase family member, NEDD8 specific.	0.843
NAE1	UBA3	ENSLACP00000011007	ENSLACP00000015907	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin like modifier activating enzyme 3.	0.999
NAE1	UCHL1	ENSLACP00000011007	ENSLACP00000012980	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin carboxyl-terminal hydrolase.	0.648
NAE1	UCHL3	ENSLACP00000011007	ENSLACP00000012875	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin carboxyl-terminal hydrolase.	0.648
NEDD8	ACO1	ENSLACP00000006393	ENSLACP00000001046	NEDD8 ubiquitin like modifier.	Aconitase 1.	0.644